Abstract: Food safety, especially in vivo situation, is essential for protecting the life and health of human. The function and impact of foods in human body are influenced by not only their chemical composition and relevant viscosity, but also their remaining quantity, location and distribution, and the metabolizing rate. This paper provides an overview to the recent research on in vivo safety of physical properties, antinutritional factors, nutrients, and the harmful components of foods in human body.

Key words: food, antinutritional factor , nutrients, harmful components, in vivo safety